Jody Jonathan Haigh, Ph.D.
Biography
Full CV
The Haigh Lab
Cutting Edge Technologies in Leukemia Research
The Haigh Lab located at the Paul Albrechtsen Research Institute at CancerCare Manitoba and the University of Manitoba uses cutting edge technologies to understand molecular mechanisms responsible for controlling blood cell development and how blood cancers arise.
We are continuing to study the role the ZEB and SNAI family of transcription factors and their roles in normal blood cell development and how when these factors become deregulated can drive aggressive forms of blood cancer.
Our Research Interests
At the Haigh Lab, we are dedicated to conducting research on molecular mechanisms responsible for controlling blood cell development and how blood cancers arise. We strive to use the latest technologies to further our understanding of this important area of study. Our team is passionate about making a difference in the lives of those affected by blood cancers and we are committed to advancing this field of science.
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In vivo Disease Modelling and Imaging
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​Epigenetic and Transcription Factor Crosstalk
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Single cell and global RNAseq analysis
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Proteomic approaches such as TurboID
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Drug Synergy screens
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Primary patient sample screens
The Haigh Lab
Dedication. Expertise. Passion.
We are an international team of investigators trying to make a difference in the lives of cancer patients. Particularly those afflicted with aggressive forms of blood cancer.
Publications
STAT5 activation promotes stemness and therapeutic resistance of leukemia-regenerating cells.
Cedric S. Tremblay, Jesslyn Saw, Jacqueline A. Boyle, Katharina Haigh, Veronique Litalien, Hannah McCalmont, Kathryn Evans, Jessica M. Salmon, Richard B. Lock, Stephen M. Jane, Jody J. Haigh, and David J. Curtis
Blood Journal, March 29, 2023 [IF=25.48]
Full Publication List
JAK/BCL2 inhibition acts synergistically with LSD1 inhibitors to selectively target ETP-ALL.
Aissa Benyoucef, Katharina Haigh, Andrew Cuddihy, Jody J. Haigh
Leukemia 2022, Oct 13. 36:2802-2816 [IF=11.53]
Jueqiong Wang, Carlos Farkas, Aissa Benyoucef, Catherine Carmichael, Katharina Haigh, Nick Wong, Danny Huylebroeck, Marc P. Stemmler, Simone Brabletz, Thomas Brabletz, Christian Nefzger, Steven Goossens, Geert Berx, Jose M. Polo, Jody J. Haigh
PLOS Biology 2021 19(9): e3001394 [IF=9.59]
Funding Organizations
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Help Solve the Puzzle
For over two decades, the Haigh Lab has been at the forefront of blood cancer research, identifying novel targets and drug combinations to help those battling this disease. We are proud of our team’s accomplishments, and we continue to explore new opportunities to further our mission. Our ongoing research projects are aimed at identifying the underlying genetic and molecular mechanisms of blood cancer and developing personalized treatments that can target blood cancer cells more effectively. Join us in our fight against cancer today.